Optimal Auditory Brainstem Implant Stimulus Rate Running Heading: Cochlear Nucleus Pulse Train Stimulation 13

An in vivo investigation of inferior colliculus single neuron responses to cochlear nucleus pulse train stimulation.

The auditory brain stem implant (ABI) is being used clinically to restore hearing to patients unable to benefit from a cochlear implant (CI). Speech perception outcomes for ABI users are typically poor compared with most CI users. The ABI is implanted either on the surface of or penetrating through the cochlear nucleus in the auditory brain stem and uses stimulation strategies developed for aud...

Hannover Medical University Clinic of Laryngology, Rhinology and Otology / University of Veterinary Medicine Hannover Investigation of Novel Auditory Implants of the Inferior Colliculus

A1 Primary auditory cortex ABI Auditory brainstem implant AMI Auditory midbrain implant CI Cochlear implant DBS Deep brain stimulation IC Inferior colliculus ICC Inferior colliculus central nucleus LFP Local field potential MSS Multi-site stimulation MUA Multi unit analysis NP NeuroProbe PSTH Post stimulus time histogram SC Superior colliculus SSS Single site stimulation

Selective Stimulation and Measurement in the Cochlear Nucleus with the Spike Microelectrode Array

Current prosthetic devices to restore hearing sense of patients with bilateral acoustic neuromas aren’t always effective, because we don’t have sufficient knowledge of the auditory pathways and the Cochlear Nucleus (CN) functions to stimulate the Cochlear Nucleus functionally. Our goals are to enhance our understanding of such functions and to develop effective stimulating strategies of the CN....

Infrared Neural Stimulation Of The Cochlear Nucleus: Towards A New Generation Of Auditory Brainstem Implants

Selective electrical stimulation of the auditory nerve activates a pathway specialized for high temporal acuity.

Deaf people who use cochlear implants show surprisingly poor sensitivity to the temporal fine structure of sounds. One possible reason is that conventional cochlear implants cannot activate selectively the auditory-nerve fibers having low characteristic frequencies (CFs), which, in normal hearing, phase lock to stimulus fine structure. Recently, we tested in animals an alternative mode of audit...